

Luca Zammataro
Bio [2004]
Luca is a postdoctoral fellow at the University of Turin, where he
specializes in molecular angiogenesis. His research topics there
include the role of collapsin response mediator proteins as signal
transducers of semaphorin signaling in endothelial cells, and
employing cellular automata to characterise integrin signaling
feedback loops. He has a M.D.-Ph.D. from the University of Catania
School of Medicine. He is interested in emergence in complex systems
and the role of NKS in biology.
Project Title
Using 3D Substitution Systems to Model Compartmentalizations and
Clusters Architectures in Nature: An NKS Approach
Project
Compartmentalization and clustering are important mechanisms present
in nature. Many processes, such as the organization of molecular
signal transductors and biological shape formation related to specific
functions, depend on them. Substitution systems are a particular class
of rules in which, at each step, each element is replaced by a new
block of elements, independently from the states of any neighbor.
For this project, a 3D substitution system was used to model
compartmentalization and clusters in natural phenomena.
The basic method is to dynamically select and collect parameters for
the substitution system rules in which one or more characteristic
clustering motifs are evidenced. Inside the patterns they produce, the
next step is to single out clusters that show spontaneous
compartmentalization and other interesting behavior.
We also propose to generate substitution rules with specific angle
distortions. This method could be applied until a pattern existing in
nature is obtained.
Favorite two-color, radius-2 rule
Rule chosen: 1659751046
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